ABSTRACT
Pulmonary embolism is a prevalent and fatal pulmonary disease. In this study, the relationships between serum highly sensitive [hs] troponin T levels and findings of ECG, colour doppler sonography of lower extremity veins venous [CDS LEV] and also arterial blood gas [ABG] in normotensive patients with acute pulmonary embolism were investigated. A cross sectional study was carried out on 33 patients with acute pulmonary embolism who were hospitalized in Emam Khomeini Hospital, Tehran University of Medical Sciences between 2009 and 2010 [mean age, 49.3; 18 male and 15 female]. [18 patients had with a normal hs-troponin T, lower than 14 pg/ml, and 15 patients had with elevated hs-troponin T.]with acute pulmonary embolism [mean age, 49.3; 18 male and 15 female] who were hospitalized in Emam Khomeini Hospital, Tehran University of Medical Sciences between 2009 and 2010 Serum hs-troponin T level was measured by ELISA highly sensitive method. The prevalence of T invert and S1Q3T3 patterns and also thrombosis in lower extremity deep venous were significantly higher in patients with elevated hs-troponin T. In addition, PCO2 and HCO3- levels were significantly lower in patients with elevated hs-troponin T levels. According to the results of the study, it seems that the elevated hs-troponin T accompanies with ECG and ABG findings and also with thrombosis in lower extremity deep venous prevalence in patients with acute pulmonary embolism
ABSTRACT
Pulmonary embolism is a prevalent and fatal pulmonary disease. In this study, the relationships of clinical and echocardiographic findings with serum troponin T level in patients diagnosed as having acute pulmonary embolism with normal pulmonary artery systolic pressure were investigated. A cross sectional study was carried out on 33 patients [18 with normal troponin T, lower than 14 pg/ml and 15 with elevated troponin T] with acute pulmonary embolism [mean age, 49.3; 18 male and 15 female], who hospitalized in Emam Khomeini Hospital, Tehran University of Medical Sciences between 2009 and 2010. Clinical and echocardiographic findings were analyzed by using x2, Exact Fisher's test and student's t-test. Serum troponin T level was measured by ELISA highly sensitive method. The prevalence of dysfunction, hypokinesia and dilatation of right ventricle, and also pulmonary hypertension in echocardiographic findings and right ventricular S3 sound in clinical finding was significantly higher in patients with elevated troponin T McConnell's sign, loud P2 sound, elevated jugular venous pulse and lowered left ventricular ejection fraction were higher in elevated troponin T patients, but there were not significant. According to results of the study, it seems that the elevated troponin T accompanies with right ventricular dysfunction signs in patients with acute pulmonary embolism